Mac OS X Server: Multiple MTAs Cannot Share TCP Port 25

Only one mail transfer agent (MTA) can use TCP port 25 at any given time.
Symptom

When you start Apple Mail Service on port 25, you see an alert that says that the port is already in use by another application (such as sendmail).


Solution

Note: Be sure that your alternate MTA is not configured to restart automatically, such as when you restart the computer.
Published Date: Feb 17, 2012