The Studio Display 21 should work with most Macintosh video cards that are DDC compliant and which support the resolutions and frequencies highlighted on the monitor's specification sheet. Connecting to the VGA connector when two connectors are present may cause display difficulties.
The Apple VGA adapter (see Figure 1) has an Apple service part number of 922-3769 and can be ordered by Apple Authorized Service Providers. The adapter has a part number of 513-0091-A molded into the grey plastic housing, and was provided with some of the early Studio Display 21 monitors.
Figure 1: VGA Adapter
As specified in the Studio Display 21 data sheet, a built-in USB port is required to use and adjust the display. The Apple display software uses the USB communication link to perform the color calibration and display adjustments.