The optimal method for removing excessive accumulations of dust is by vacuuming it up with a static protected vacuum designed for use with sensitive electronic components. An alternate method is compressed air such as that available in small aerosol cans at electronics retailers.
When using compressed air to remove dust, it is important to follow the instructions accompanying the product. Special care should be taken to always hold the can upright and not to shake the contents while spraying. Condensation and possible component damage may occur should these products be misused.
A gentle stream of air delivered in a series of short bursts should be all that is necessary to remove the majority of any accumulation, it is not necessary to remove all of the accumulation. Direct the stream of air away from mechanical components such as disk drives, power supplies, and expansion slots to prolong their life.