Macintosh: Possible Cures for Jumpy Mouse Pointer
If the jumpiness persists, the small rollers inside the mouse may be dirty. Remove the mouseball retaining ring by turning it counter-clockwise one quarter turn. The retainer will pop off and the mouse ball will come out.
Check the black rollers for contamination. If you notice a buildup of dirt on the rollers, clean them with your fingernail or other non-metal tool. The mouseball should also be cleaned periodically to ensure it will roll smoothly and grip the rollers inside the mouse. Use a soft rag and water or a mild soap to clean the ball. Rinse it thoroughly before reinstalling it into the mouse.
If the mouse continues to act up, it may be in need of replacement. Try the mouse on another computer, or try a different mouse on your computer to determine where the fault lies. Contact your local Apple Authorized Service Provider for a replacement mouse.
Refer to TIL article 6491: "How to Clean a Mouse" for complete instructions on cleaning Apple mice.