Yes, both the AppleCD 600i and 600e drives are supported using the DOS Compatible card. However you must use the Apple CD-ROM extension v5.1.1, PC Setup 1.0.7, and System 7.5.1. Both the CD-ROM Setup 5.1.1 and PC Setup 1.0.7 are available from online services. PC Setup 1.0.7 is only designed for the DOS Compatibility Card on Power Macintosh, and Macintosh 630 family computers. Apple does not recommend or support PC Setup 1.0.7 on Centris or Quadra 610 computers with a DOS Compatibility Card.
The following computers are in the Macintosh 630 family: Performa 630, Performa 635, Performa 636, Performa 637, Performa 638, Performa 640, LC 630, and Quadra 630.
There are some types of compact discs which are not supported in the MS-DOS/Windows enviroment, including Photo CD, and multisession compact discs. In addition to these types of discs, you cannot use multiple CD-ROM drives in the MS-DOS/Windows environment.
Audio CDs cannot be controlled from both the Windows and Macintosh environment at the same time.
The MS-DOS sets up a drive letter (E:) for a CD-ROM drive, even if there is not a drive attached. If you do not have a CD-ROM drive connected to your computer, you can gain additional memory by removing drive setup strings in the CONFIG.SYS and AUTOEXEC.BAT files.
What to Change
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AUTOEXEC.BAT
REM LH C:\\DOS\\MSCDEX /D:CDDRVR /L:E
CONFIG.SYS
REM DEVICE=C:\\Apple\\CDROM.SYS /D:CDDRVR
The REM in front of the command makes MS-DOS ignore the line.