AppleWorks 2.0 requires 128K of memory to run successfully; an Apple IIe with an 80-column card installed will display the message "AppleWorks can only be used on systems with 128K of memory" when later versions of the AppleWorks program are booted.
AppleWorks 2.0 can use as a RAMDisk the 256K to 1MB of memory in the Memory Expansion Cards designed for and respectively used in the Apple IIe, Apple IIGS, or the Apple IIc with a memory expansion slot. AppleWorks 2.0 will not use an Apple IIe Memory Expansion Card in an Apple IIGS.