This will happen anytime you boot with extensions off, via the Shift key option, on any computer running Open Transport. Open Transport is turned off, and therefore, the AppleTalk Control Panel becomes inactive and so it cannot be opened (or activated). When running systems in the Open Transport mode, the Extensions Manager should be used to turn off extensions instead of the Shift key option.
NOTE: This does not occur if you select "All OFF" in the Extensions Manager. If you do select "ALL OFF," then all printer drivers will be de-activated.