This combination seems to result in random, intermittent problems with MacDraw II files. When you re-save an existing MacDraw II document, the new file may save with a different name. Or, the dialog box "File Not Found" may appear.
This problem has not been tested or confirmed by Claris. However, customers report that removing GateKeeper eliminates the problem. (The GateKeeper info. file does admit to an incompatibility with MacDraw II).
This problem does NOT seem to be present with the GateKeeper Aid INIT, which is different than GateKeeper.