An application that is not created to take advantage of the Power Macintosh processor will require more memory in order to function on the Power Macintosh.
If you have installed an application on a Power Macintosh, and it does not open as expected, check a few possibilities:
1) Is the application compatible with Apple System 7.1 or System 7.5 software?
Often, old software will be moved from an older macintosh onto a Power Macintosh. Be very careful that your software is current enough to run on any Macintosh running System 7.1 or higher software.
2) Was the application created to run on a Power Macintosh?
If a Macintosh application is called "Power PC Native," it should function without issues on any Power Macintosh. Check for INIT, Extension or Control Panel conflicts if you have added any software to your system folder. If you cannot discover a issue, contact the application's manufacturer.
3) Have you allocated more RAM for non-native products?
If you are using a System 7.1 or System 7.5 compatible product, and your product still does not open properly on a Power Macintosh, verify that it is using enough computer RAM.
To check for available RAM, first quit all open applications. Then select About this Macintosh under the Apple menu. An number labeled Largest Unused Block will show you how much memory is available beyond the system requirements. You can give your software applications up to that amount, if needed.
To adjust the RAM requirements of a product, again verify that the product is not running (look under the icon of the Application menu in the upper right corner of your screen. If the product is listed, select it from the list, then select Quit from the File menu.) Single-Click (click only once) on the application's icon on the hard drive. Then select Get Info from the File menu. The info window should show you Suggested, Minimum, and Preferred memory requirements. For non-native applications, you will want to increase the Minimum and Preferred numbers higher than the Suggested number. (I arbitrarily double the Suggested value to set the minimum, and triple the suggested value to set the preferred. For a 1000K suggested, I set the minimum to 2000 and the preferred to 3000. You may wish to try various settings to see what best suits your other memory needs.)