It sounds like the application is making serial communication calls directly to the PowerBook 170's serial chip. An application should use normal communications calls to talk to the serial driver; it should never attempt to get direct access to the SCC hardware.
The serial chip is turned off when not in use (in order to conserve power). If your application makes normal serial communications calls, the serial driver knows how to turn the serial chip back on. However, an application that attempts to go directly to the serial chip will wind up talking to the chip when it's turned off, resulting in a loss of communication.
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